Analytical tools Early access

Horizon Oncology
Modelling Platform

An environment for developing and sharing economic evaluations

One environment that takes an oncology indication from survival evidence, through treatment and disease costing, to economic evaluation and professional reporting. Built for health economists by health economists.

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The platform

An integrated modelling platform for oncology indications

Integrated modelling platforms are health economic models designed to span multiple indications and interventions. They offer an efficient alternative to conventional single-application modelling, and offer a reduced burden compared to the inherent structural complexity required by more flexible 'all-purpose' model builders.

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Design principles

Integrated modelling platform

Systematic

Deterministic

Reproducible

Accessible

Scalable

While model concepts and inputs vary by project, many underlying processes are highly consistent. That creates the opportunity to build workflows that are fast and flexible while staying reliable and auditable.

At a glance

  • Build a complete cost-effectiveness analysis in the browser, with nothing to install
  • Extrapolate survival data from multiple forms of aggregate-level summary data or patient-level data
  • Cost treatments with full regimen logic, or with simple per-period prices, and generate comprehensive EJP summaries
  • Run comprehensive sensitivity and survival scenario analyses
  • Generate Word reports and PowerPoint decks automatically
  • Export analyses to Excel
  • Load pre-defined input templates and save, reload or duplicate whole analyses
  • Share completed analysis with colleagues in your organisation
  • Unit tests applied to functions and statistical processes to ensure validity and accuracy

Platform design

Six steps from evidence to shared analysis

The platform is built around an organised workflow with sections unlocked as their prerequisites are met, with the platform informing users of what is still outstanding.

  1. Indication specification

    Define the indication and the relevant treatments, along with the patient profile.

  2. Survival analysis

    Undertake aggregate- or IPD-level survival analysis, depending on the available evidence.

    Aggregate-level survival analysis

    • Digitised KM curves
    • Landmark survival analysis
    • User-defined parametric models
    • Survival curve upload
    • Hazard ratios

    IPD-level survival analysis

    • KM evaluation
    • Proportional hazards
    • Parametric models
    • Spline models
    • Cure models

  3. Economic modelling

    Populate health economic inputs (treatment costs, disease management costs, utilities and adverse events) and undertake cost-effectiveness analysis.

    • Cost-effectiveness
    • Clinical outcomes
    • Economically justifiable pricing
    • Fully incremental analysis

  4. Sensitivity analysis

    Explore the sensitivity of modelled outcomes to different input settings and values, and comprehensively evaluate the impact of alternative survival modelling profiles and assumptions.

    • OWSA
    • Survival scenario analyses
    • Economically justifiable pricing

  5. Automated reporting

    Generate Word and slide deck output automatically from the analysis, alongside CSV exports of input profiles and model trace output.

  6. Sharing analyses

    Share a completed analysis with colleagues in your organisation. Recipients open it as a read-only snapshot and can save their own copy to work from, so the original is never altered by accident.

Roadmap

What is coming next

The platform is developed continuously. These are the next additions.

  1. September

    Budget impact and pricing forecast module

  2. Planned

    Treatment response stratification

  3. Planned

    Companion HTA-ready Excel model

  4. Planned

    Automated AI input population

Access

Two ways to use it

Subscribe to the platform hosted by us, or buy it and run it on your own servers. The application is identical either way - the difference is where your data lives.

Option one

Subscription

Use the platform on our managed infrastructure, hosted on Microsoft Azure in the UK. Sign-in runs through Microsoft Entra ID, with multi-factor authentication enforced and access granted only to named users. We take care of hosting, updates, backups, monitoring and support.

  • Nothing to deploy or maintain
  • Updates and new capability as they ship for no extra cost
  • Ongoing support
  • Priced by users and term

Option two

Purchase and self-host

Purchase the platform and deploy it directly inside your own organisation. It ships as a containerised application that runs on your servers, behind your network and your identity provider so that analyses and confidential data never leave your infrastructure.

  • Data never leaves your environment
  • Your network, your identity provider, your policies
  • Deployment support and handover, or a fully supported licence
  • One-time purchase cost

Want a closer look?

We will walk your team through a real analysis, answer the methodological questions, and set out what subscription or self-hosting would look like for you.

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